Diseases Treated with Stem Cells

Diseases Treated with Stem Cells

Stem cell transplants have been used since the 1960’s to treat a variety of diseases. In 1988 cord blood stem cells were used for the first time in hematopoietic (blood) stem cell transplantation. Umbilical cord blood stem cells have now been used in over 3,500 transplants worldwide as a valuable alternative to traditional sources of hematopoietic stem cells. Utilizing the process of stem cell banking, cord blood stem cells also show great promise for potential future applications including treatment and repair of non-hematopoietic tissues, gene therapies, mini-transplants, among others.

* Current Stem Cell Applications
* Potential Future Applications
* Download list in pdf format

Current Stem Cell Applications

Acute Leukemia’s
Acute Lymphoblast Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Biphenotypic Leukemia
Acute Undifferentiated Leukemia

Chronic Leukemia’s
Chronic Myelogenous Leukemia (CML)
Chronic Lymphocytic Leukemia (CLL)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes
Refractory Anemia (RA)
Refractory Anemia with Ringed Sideroblasts (RARS)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Chronic Myelomonocytic Leukemia (CMML)

Stem Cell Disorders
Aplastic Anemia (Severe)
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia

Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (myelofibrosis)
Polycythemia Vera
Essential Thrombocythemia

Lymphoproliferative Disorders
Non-Hodgkin's Lymphoma
Hodgkin's Disease

Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Other Inherited Disorders
Lesch-Nyhan Syndrome
Cartilage-Hair Hypoplasia
Glanzmann Thrombasthenia
Osteopetrosis
Adrenoleukodystrophy

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

Inherited Metabolic Disorders
Mucopolysaccharidoses (MPS)
Hurler's Syndrome (MPS-IH)
Scheie Syndrome (MPS-IS)
Hunter's Syndrome (MPS-II)
Sanfilippo Syndrome (MPS-III)
Morquio Syndrome (MPS-IV)
Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Adrenoleukodystrophy
Mucolipidosis II (I-cell Disease)
Krabbe Disease
Gaucher's Disease
Niemann-Pick Disease
Wolman Disease
Metachromatic Leukodystrophy

Histiocytic Disorders
Familial Erythrophagocytic Lymphohistiocytosis
Histiocytosis-X
Hemophagocytosis

Inherited Erythrocyte Abnormalities
Beta Thalassemia Major
Sickle Cell Disease

Inherited Immune System Disorders
Ataxia-Telangiectasia
Kostmann Syndrome
Leukocyte Adhesion Deficiency
DiGeorge Syndrome
Bare Lymphocyte Syndrome
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Absence of T & B Cells SCID
Absence of T Cells, Normal B Cell SCID
Common Variable Immunodeficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Plasma Cell Disorders
Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia
Amyloidosis

Other Malignancies
Ewing Sarcoma
Neuroblastoma
Renal Cell Carcinoma
Retinoblastoma

Potential Future Stem Cell Applications

Alzheimer’s Disease
Cardiac Disease
Diabetes
Lupus
Multiple Sclerosis
Muscular Dystrophy
Parkinson’s Disease
Rheumatoid Arthritis
Spinal Cord Injury
Stroke